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SAM-Spec Mix : real-time Multi-point Monitoring for Mixing and Blending

SAM-Spec Mix : real-time Multi-point Monitoring for Mixing and Blending - CHAUVIN ARNOUX

SAM-Spec Mix : real-time Multi-point Monitoring for Mixing and Blending - Spectroscopy

SAM-Spec Mix : real-time Multi-point Monitoring for Mixing and Blending

Spectroscopy

“ ● SAM-Spec use a patented NIR-SRS optical technology ● Scattering of photons at different wavelengths provides physical information ● Absorption provides the chemical information on the product ● Comparison of signals between different probes provides homogeneity level within the tank ”

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Presentation

The only solution is to perform multi-point analysis inside and during the process. SAM-Spec® Mix is the only commercially available solution able to provide the required QC. Processing times will be faster with significant cost and processing benefits.

Single vessel inspection
● Immediate analysis of multiple critical points.
● Automatic evaluation of homogeneity.
● Detection of sedimentation
● Mapping of mean particle size vs/depth
● Mapping of chemical concentration vs/depth.
● Ideal in process dev for mixing design (blade shape/speed/vessel) and scale-up phase.

Continuous inspection from mixing to filling
● Full inspection of the vessel, filling, processing & packaging.
● Sedimentation/unmixing identification within the pipe.
● Optimization of cleaning time for the full line.
● Particularly suited to flexible production lines: switch time and validation of changes from product A to B
● Product identification and flow monitoring in continuous processes

Technical features

Turbidity range: 0->15,000 NTU Concentration accuracy: Typical 1% to 100 % Mean particle size: Min 200nm to 1,000μm 21 CFR Part 11 compliance Full IQ/OQ/PQ support GMP compliance

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