JRS RETTENMAIER France

Sodium Stearyl Fumarate : PRUV®

Sodium Stearyl Fumarate : PRUV® - JRS RETTENMAIER France

Sodium Stearyl Fumarate : PRUV® - Special chemistry

Sodium Stearyl Fumarate : PRUV® - produit présenté par JRS RETTENMAIER France

Sodium Stearyl Fumarate : PRUV®

Special chemistry

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Presentation

PRUV^® is a tablet lubricant designed for formulations in which other lubricants lead to formulation and/or manufacturing challenges. As opposed to the frequently used lubricant, magnesium stearate, PRUV^® offers the following advantages:

High degree of API compatibility*
Robustness to over-lubrication
No adverse effect on bioavailability
Improved appearance of effervescent solutions.

PRUV^® helps to accelerate product development and is particularly well suited for high-speed direct compression of tablets.

*Reported API incompatibilities with magnesium stearate include: Azathioprin, Cefaclor, Cilazapril, Clopidogrelacetate, Dicofenac, Fosinopril, Ibuprofen, Ketorolac, Levofloxacin, Nifedipine, Omeprazole, Ramipril, and Trandolapril.

PRUV^® offers:

Improved drug stability
Faster dissolution rates
Harder tablets
Protection from over-blending
Faster formulation development and scale-up
Enhanced lubrication efficiency

http://www.jrspharma.com/pharma_en/products-services/excipients/lubricants/pruv.php