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Automated Microwave Peptide Synthesizer : Liberty Blue HT12™

Laboratory instruments

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The Liberty Blue HT12 Automated Microwave Peptide Synthesizer is the gold standard for peptide synthesis. It features unmatched 4-minute cycle times along with a 90% solvent reduction based on High Efficiency Solid Phase Peptide synthesis (HE-SPPS) developed in 2013.

The HT12 upgrade for Liberty Blue allows for the fast sequential synthesis of up to 12 peptides which offers significant advantages over traditional parallel peptide synthesizers.

This system is utilized in hundreds of laboratories worldwide and provides unparalleled peptide quality based on its unique methodology and use of microwave energy.

The Liberty Blue HT12 features the latest in engineering for fluidic deliveries, true internal temperature feedback control, and software control with 21 CFR Part 11 compliance.

Automated synthesize of up to 12 peptides (individual 20mer’s completed every 1.5 hours). Liberty Blue HT12 sequential batch synthesis even keeps up with conventional parallel systems.

The fastest and most complete coupling.Stabilizes acid sensitive linkages which are problematic for standard carbodiimide chemistry (phospho, glyco, hyper-acid linkages).

Unmatched low-level of epimerization for all 20 amino acids due to faster activation (faster o-acylisourea formation).

Judicious use of solvents and reagents from optimized washing and synthetic protocols. Superior system design minimizes calibration, cleaning, and maintenance needs.

The most advanced software for simple and flexible control.


Automated programming of standard and complex peptides (branched, cyclized, disulfide bonding)
21 CFR Part 11 compliance including full run history and method reports
Integrated real-time camera into microwave cavity

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