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Automated Microwave Peptide Synthesizer : Liberty PRIME™

Laboratory instruments

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The Liberty PRIME peptide synthesizer is the most advanced platform available for microwave peptide synthesis. It features a revolutionary one-pot deprotection and coupling process allowing for a remarkable 2 minute cycle time with only 8.5mL waste per cycle (at 0.1 mmol).

The ultra fast sequential synthesis workflow with Liberty PRIME dramatically outperforms traditional parallel peptide synthesizers.

Based on a revolutionary one-pot deprotection and coupling process, along with the patented CarboMAX coupling chemistry, an unprecedented 2 minute cycle time is achieved.

By using a patented process that reuses the coupling solution for the subsequent deprotection step, along with a system design that requires no internal washing the Liberty PRIME reduces waste to unimaginable levels.

All reagents are delivered either by pressure-based Flex-Add delivery system or precalibrated pumping system.

This means you can always be confident that the right amount of each reagent is delivered every time at volumes as low as 0.25mL. The Liberty PRIME provides calibration-free reagent delivery that is ideal for GMP processes.

The fastest and most complete coupling.
Stabilizes acid sensitive linkages which are problematic for standard carbodiimide chemistry (phospho, glyco, hyper-acid linkages).
Unmatched low-level of epimerization for all 20 amino acids due to faster activation (faster o-acylisourea formation).



 

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